SCHEMBL21728102

SCHEMBL21728102

C#CCCc1cc(F)cc(F)c1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.38
DAO P14920 2/20 0.36
CYP17A1 P05093 1/20 0.36
CYP21A2 P08686 1/20 0.36
CYP11B1 P15538 1/20 0.36
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31
PYCR1 P32322 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13099035 0.79 TAAR1 (0.57) IDO1DAOMAOAMAOBTAAR1
SCHEMBL4847285 0.76 DAO (0.40) IDO1DAOCYP17A1CYP21A2CYP11B1
SCHEMBL10546321 0.76 MEN1 (0.52) IDO1DAOCYP17A1CYP21A2CYP11B1
SCHEMBL5546168 0.76 DAO (0.40) IDO1DAOCYP17A1CYP21A2CYP11B1
SCHEMBL1311590 0.76 TAAR1 (0.50) IDO1MAOAMAOBPYCR1TAAR1
SCHEMBL16105495 0.76 IDO1 (0.50) IDO1DAOCYP17A1CYP21A2CYP11B1
SCHEMBL14012242 0.71 ACHE (0.39)
SCHEMBL31650900 0.69 IDO1 (0.44) IDO1DAOCYP17A1CYP21A2CYP11B1
SCHEMBL14012243 0.68 MEN1 (0.30)
SCHEMBL294824 0.67 IDO1 (0.42) IDO1DAOCYP17A1CYP21A2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611166-A1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2020-02-19 EP disclosed