Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 19/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544128 | 0.84 | HCAR3 (0.73) | HCAR3HPGDHCAR2NAMPT | |
| SCHEMBL6044058 | 0.84 | HCAR3 (1.00) | HCAR3HPGDHCAR2 | |
| SCHEMBL6044508 | 0.82 | HCAR3 (1.00) | HCAR3HPGDHCAR2 | |
| SCHEMBL6033322 | 0.82 | HCAR3 (0.74) | HCAR3HPGDHCAR2NAMPT | |
| SCHEMBL23084792 | 0.81 | HCAR3 (0.72) | HCAR3HPGDHCAR2 | |
| SCHEMBL6044288 | 0.81 | HCAR3 (0.78) | HCAR3HPGDHCAR2 | |
| SCHEMBL6044297 | 0.81 | HCAR3 (0.72) | HCAR3HPGDHCAR2NAMPT | |
| SCHEMBL6043680 | 0.81 | HCAR3 (0.68) | HCAR3HPGDHCAR2 | |
| SCHEMBL6044303 | 0.81 | HCAR3 (1.00) | HCAR3HPGDHCAR2NAMPT | |
| SCHEMBL6043812 | 0.81 | HCAR3 (0.68) | HCAR3HPGDHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3094626-B1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS AS RXR AGONISTS | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2020-02-19 | — | — | EP | disclosed |