Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 13/20 | 1.00 |
| ▸ | NAMPT | P43490 | 1/20 | 0.61 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.60 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.60 |
| ▸ | MME | P08473 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15687303 | 0.85 | HCAR3 (0.74) | HCAR3NAMPTGRM2SLC9A1MME | |
| SCHEMBL6044207 | 0.85 | HCAR3 (0.74) | HCAR3NAMPTMMEHPGDHCAR2 | |
| SCHEMBL6044668 | 0.84 | HCAR3 (0.77) | HCAR3NAMPTHPGDHCAR2 | |
| SCHEMBL6043919 | 0.84 | HCAR3 (1.00) | HCAR3NAMPTMMEALDH1A1 | |
| SCHEMBL6919405 | 0.83 | HCAR3 (0.71) | HCAR3GRM2SLC9A1MME | |
| SCHEMBL16904968 | 0.82 | HCAR3 (0.70) | HCAR3NAMPTGRM2MME | |
| SCHEMBL6033322 | 0.81 | HCAR3 (0.74) | HCAR3NAMPTHPGDHCAR2 | |
| SCHEMBL6044058 | 0.81 | HCAR3 (1.00) | HCAR3HPGDHCAR2 | |
| SCHEMBL21728478 | 0.81 | HCAR3 (0.73) | HCAR3NAMPTHPGDHCAR2 | |
| SCHEMBL4544128 | 0.81 | HCAR3 (0.73) | HCAR3NAMPTHPGDHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060122240-A1 | Benzotriazoles and methods of prophylaxis or treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. (US) | 2006-06-08 | — | — | US | claimed |
| US-20060122240-A1 | Benzotriazoles and methods of prophylaxis or treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. (US) | 2006-06-08 | — | — | US | disclosed |
| WO-2004041274-A1 | BENZOTRIAZOLES AND METHODS OF PROPHYLAXIS OR TREATMENT OF METABOLIC-RELATED DISORDERS THEREOF | ARENA PHARMACEUTICALS, INC. (US) | 2004-05-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122240-A1 | Benzotriazoles and methods of prophylaxis or treatment of metabolic-related disorders thereof | GCGR, GPR119, HMGCR | HCAR3 85/4885NAMPT 1010/4885GRM2 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.