SCHEMBL21728643

SCHEMBL21728643

C[C@@H]1CC[C@@H](C(C)(C)O)CC1=O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
KMT2A Q03164 1/20 0.34
CES2 O00748 2/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10593768 1.00 CA1 (0.35) CA1CA2CA4KMT2ACES2
SCHEMBL23015539 1.00 CA1 (0.35) CA1CA2CA4KMT2ACES2
SCHEMBL9539936 0.83 CA1 (0.38) CA1CA2CA4KMT2A
SCHEMBL7827236 0.80 CA1 (0.33) CA1CA2CA4KMT2A
SCHEMBL8022375 0.79 CA1 (0.35) CA1CA2CA4KMT2A
Acetic Acid SCHEMBL10470986 0.79 GLA (0.35) CA1CA2CA4KMT2ALMNA
SCHEMBL3230995 0.76 KDM4E (0.31) CA1CA2CA4
Guaiol SCHEMBL18965701 0.72 LMNA (0.35) CES2LMNA
Guaiol SCHEMBL14871827 0.72 LMNA (0.35) CES2LMNA
Guaiol SCHEMBL16207769 0.72 LMNA (0.35) CES2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11358944-B2 Anxiolytic deuterated compound and medical use thereof BEIJING JUNKE HUAYUAN MED TECH CO., LTD. (CN) 2022-06-14 US disclosed
EP-3611170-B1 DEUTERATED COMPOUNDS AND MEDICAL USE THEREOF AS ANTIANXIETY AGENTS BEIJING JUNKE HUAYUAN MED TECH CO LTD (CN) 2022-01-26 EP disclosed
US-20200095219-A1 ANXIOLYTIC DEUTERATED COMPOUND AND MEDICAL USE THEREOF BEIJING JUNKE HUAYUAN MED TECH CO., LTD. (CN) 2020-03-26 US disclosed
EP-3611170-A1 ANTIANXIETY DEUTERATED COMPOUNDS AND MEDICAL USE THEREOF Jingluweidai Information Consulting Service (Beijing) Co Ltd (CN) 2020-02-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200095219-A1 ANXIOLYTIC DEUTERATED COMPOUND AND MEDICAL USE THEREOF DRD1, DRD2, DRD4 CA1 1819/4885CA2 3460/4885CA4 2330/4885
US-11358944-B2 Anxiolytic deuterated compound and medical use thereof DRD1, DRD2, DRD4 CA1 1819/4885CA2 3460/4885CA4 2330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.