Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2458495 | 0.84 | AHR (0.67) | AHRHSD11B1TP53NPC1RAB9A | |
| SCHEMBL2463985 | 0.78 | AHR (0.53) | AHRHSD11B1TP53NPC1RAB9A | |
| SCHEMBL31339480 | 0.78 | AHR (0.63) | AHRHSD11B1TP53NPC1RAB9A | |
| SCHEMBL21728896 | 0.75 | AHR (0.48) | AHRTP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4450464 | 0.74 | AHR (0.71) | AHRHSD11B1TP53NPC1RAB9A | |
| SCHEMBL15637337 | 0.74 | AHR (0.59) | AHRHSD11B1TP53NPC1RAB9A | |
| SCHEMBL1045006 | 0.74 | AHR (0.57) | AHRHSD11B1TP53SRD5A2HSP90AA1 | |
| SCHEMBL2908267 | 0.73 | AHR (1.00) | AHRHSD11B1TP53NPC1RAB9A | |
| SCHEMBL2933108 | 0.72 | AHR (0.67) | AHRHSD11B1TP53NPC1RAB9A | |
| SCHEMBL13239270 | 0.72 | PTGES2 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773616-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-19 | — | — | EP | disclosed |