SCHEMBL4450464

SCHEMBL4450464

Clc1cc(Cl)cc(-c2ccc(Cl)cc2Cl)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.71
TP53 P04637 3/20 0.48
SRD5A2 P31213 1/20 0.47
HSD11B1 P28845 3/20 0.45
TSHR P16473 4/20 0.43
RAB9A P51151 3/20 0.43
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 2/20 0.43
NPC1 O15118 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HPGD P15428 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
CYP3A4 P08684 1/20 0.42
KDM4E B2RXH2 2/20 0.41
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12581336 0.85 AHR (0.53) AHRTP53SRD5A2HSD11B1TSHR
SCHEMBL2908267 0.83 AHR (1.00) AHRTP53SRD5A2HSD11B1TSHR
SCHEMBL2933108 0.82 AHR (0.67) AHRTP53SRD5A2HSD11B1TSHR
SCHEMBL2235302 0.81 AHR (0.59) AHRTP53SRD5A2HSD11B1TSHR
SCHEMBL29624840 0.81 AHR (0.64) AHRTP53SRD5A2HSD11B1TSHR
SCHEMBL464507 0.81 AHR (0.64) AHRTP53SRD5A2HSD11B1TSHR
SCHEMBL4459046 0.80 TP53 (0.48) AHRTP53TSHRRAB9AALDH1A1
SCHEMBL31339480 0.79 AHR (0.63) AHRTP53SRD5A2HSD11B1TSHR
SCHEMBL4452962 0.79 AHR (0.56) AHRTP53SRD5A2HSD11B1TSHR
SCHEMBL510771 0.78 AHR (0.61) AHRTP53SRD5A2HSD11B1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-112384917-B Mirror assembly including scanning device 金泰克斯公司 2024-08-06 CN disclosed
CN-117188872-A Intelligent lock and lock body 鹿客科技(北京)股份有限公司 2023-12-08 CN disclosed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
CN-110607279-B 3D culture system of primary tumor cells, and culture method and application thereof 深圳优圣康医学检验实验室 2023-09-19 CN disclosed
CN-116234161-A Circuit board and computing device 超聚变数字技术有限公司 2023-06-06 CN disclosed
CN-108068682-B Lighting system with indicator device 福特环球技术公司 2023-03-24 CN disclosed
CN-217783181-U Intelligent lock and lock body 云丁网络技术(北京)有限公司 2022-11-11 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed