Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20003496 | 0.81 | AHR (0.52) | AHRCYP1A2ALOX5MAOBSMN1; SMN2 | |
| SCHEMBL29097690 | 0.81 | AHR (0.52) | AHRCYP1A2ALOX5MAOBSMN1; SMN2 | |
| SCHEMBL10018705 | 0.81 | ACHE (0.43) | CYP1A2SMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL13614626 | 0.81 | ACHE (0.43) | CYP1A2SMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL13471707 | 0.80 | ALOX5 (0.43) | AHRCYP1A2ALOX5MAOBALDH1A1 | |
| SCHEMBL18673225 | 0.80 | HDAC1 (0.42) | ALDH1A1ESR1ESR2TP53TSHR | |
| SCHEMBL7769653 | 0.78 | ALOX5 (0.50) | AHRCYP1A2ALOX5MAOBSMN1; SMN2 | |
| SCHEMBL13239270 | 0.78 | PTGES2 (0.37) | ALOX5ALDH1A1MAPK1 | |
| SCHEMBL13105050 | 0.77 | ESR1 (0.56) | ALOX5ESR1ESR2KIF11 | |
| SCHEMBL13878995 | 0.76 | AHR (0.52) | AHRCYP1A2ALOX5SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773616-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-19 | — | — | EP | disclosed |