Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 5/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | CA9 | Q16790 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210090 | 0.86 | TDP1 (0.76) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL9173996 | 0.85 | CA14 (0.55) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL134329 | 0.84 | TDP1 (0.85) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL137629 | 0.84 | TDP1 (0.85) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL343629 | 0.84 | TDP1 (0.85) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL136815 | 0.84 | TDP1 (0.85) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL3025184 | 0.84 | TDP1 (0.85) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL5162656 | 0.84 | TDP1 (0.85) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL2032859 | 0.84 | EGLN1 (0.61) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL140853 | 0.84 | TDP1 (0.85) | TDP1MAOAMAOBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11547674-B2 | Protein-polymer hybrid biomaterials | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-01-10 | — | — | US | disclosed |
| US-20200054574-A1 | PROTEIN-POLYMER HYBRID BIOMATERIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054574-A1 | PROTEIN-POLYMER HYBRID BIOMATERIALS | LDHA, LDHB, STIP1 | TDP1 3732/4885MAOA 4583/4885MAOB 4539/4885 |
| US-11547674-B2 | Protein-polymer hybrid biomaterials | LDHA, LDHB, STIP1 | TDP1 3732/4885MAOA 4583/4885MAOB 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.