Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21729638 | 0.88 | RORC (0.42) | RORCNPY5RL3MBTL1 | |
| SCHEMBL21729689 | 0.87 | RORC (0.58) | RORC | |
| SCHEMBL21729690 | 0.87 | RORC (0.58) | RORC | |
| SCHEMBL21729713 | 0.82 | RORC (0.50) | RORC | |
| SCHEMBL21729660 | 0.71 | RORC (0.56) | RORC | |
| SCHEMBL21729719 | 0.71 | RORC (0.55) | RORC | |
| SCHEMBL29758649 | 0.70 | RORC (1.00) | RORC | |
| SCHEMBL18939880 | 0.70 | RORC (1.00) | RORC | |
| SCHEMBL18961493 | 0.69 | RORC (0.84) | RORC | |
| Hydrochloric Acid SCHEMBL18940116 | 0.69 | RORC (0.98) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035556-A1 | NOVEL HETEROAROMATIC MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA | LEO PHARMA A/S (DK) | 2020-02-20 | — | — | WO | disclosed |