Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | GCG | P01275 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | GIPR | P48546 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21729634 | 0.88 | RORC (0.53) | RORCNPY5RL3MBTL1 | |
| SCHEMBL21729714 | 0.82 | GHSR (0.40) | RORC | |
| SCHEMBL21729689 | 0.74 | RORC (0.58) | RORC | |
| SCHEMBL21729690 | 0.74 | RORC (0.58) | RORC | |
| SCHEMBL21729656 | 0.72 | RORC (0.37) | RORCGCGGCGRGIPR | |
| SCHEMBL21729721 | 0.72 | RORC (0.41) | RORC | |
| SCHEMBL21729657 | 0.71 | RORC (0.41) | RORC | |
| SCHEMBL21729713 | 0.71 | RORC (0.50) | RORC | |
| SCHEMBL21729711 | 0.68 | CCR5 (0.38) | CCR5CRHR1 | |
| SCHEMBL21723548 | 0.64 | KDM4E (0.39) | CCR5MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035556-A1 | NOVEL HETEROAROMATIC MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA | LEO PHARMA A/S (DK) | 2020-02-20 | — | — | WO | disclosed |