SCHEMBL21730592

SCHEMBL21730592

C=Cc1ccc(-c2ccc3c(c2)C2(c4ccccc4-c4ccc(Br)cc42)c2ccccc2-3)cc1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 15/20 0.41
HDAC2 Q92769 1/20 0.32
TDP2 O95551 1/20 0.32
SLC6A3 Q01959 1/20 0.32
PTPRC P08575 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21064258 0.91 PDK2 (0.43) PDK2HDAC2ALDH1A1TSHR
SCHEMBL23134181 0.89 PDK2 (0.40) PDK2TDP2
SCHEMBL14427824 0.88 PDK2 (0.45) PDK2PTPRCALDH1A1TSHR
SCHEMBL12781932 0.87 PDK2 (0.49) PDK2TDP2SLC6A3PTPRCALDH1A1
SCHEMBL14269410 0.87 PDK2 (0.51) PDK2PTPRC
SCHEMBL6292662 0.87 PDK2 (0.51) PDK2PTPRC
SCHEMBL2395101 0.86 PDK2 (0.41) PDK2TDP2SLC6A3PTPRCALDH1A1
SCHEMBL14189338 0.85 PDK2 (0.50) PDK2TDP2ALDH1A1
SCHEMBL30823857 0.85 PDK2 (0.50) PDK2TDP2ALDH1A1
SCHEMBL26155068 0.85 PDK2 (0.50) PDK2TDP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3763750-B1 POLYMER, MONOMER, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG CHEMICAL LTD (KR) 2023-07-19 EP disclosed
US-11706970-B2 Polymer, coating composition comprising same, and organic light emitting device using same LG CHEM, LTD. 2023-07-18 US disclosed
US-11706970-B2 Polymer, coating composition comprising same, and organic light emitting device using same LG CHEM, LTD. 2023-07-18 US disclosed
US-20230043088-A1 Organic Light Emitting Device LG CHEM, LTD. (KR) 2023-02-09 US disclosed
EP-3763750-A1 POLYMER, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2021-01-13 EP disclosed
WO-2020036459-A1 POLYMER, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11706970-B2 Polymer, coating composition comprising same, and organic light emitting device using same CRY1, GPS1, SEM1 PDK2 3132/4885HDAC2 2650/4885TDP2 2952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.