Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9425124 | 0.92 | ALDH1A1 (0.45) | ALDH1A1THRBBLMPMP22NPSR1 | |
| Bicarbonate SCHEMBL9425333 | 0.92 | ALDH1A1 (0.45) | ALDH1A1THRBBLMPMP22NPSR1 | |
| Bicarbonate SCHEMBL5577148 | 0.92 | ALDH1A1 (0.45) | ALDH1A1THRBBLMPMP22NPSR1 | |
| Acetic Acid SCHEMBL28861257 | 0.92 | ALDH1A1 (0.45) | ALDH1A1THRBBLMPMP22NPSR1 | |
| Acetone SCHEMBL28113495 | 0.88 | ALDH1A1 (0.47) | ALDH1A1THRBBLMPMP22NPSR1 | |
| Carbamic Acid SCHEMBL8556803 | 0.86 | ALDH1A1 (0.41) | ALDH1A1THRBBLMPMP22NPSR1 | |
| SCHEMBL7827565 | 0.85 | — | — | |
| SCHEMBL65570 | 0.85 | — | — | |
| SCHEMBL11123616 | 0.85 | ALDH1A1 (0.56) | ALDH1A1THRBBLMPMP22NPSR1 | |
| SCHEMBL11123615 | 0.85 | ALDH1A1 (0.56) | ALDH1A1THRBBLMPMP22NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519560-B1 | COPOLYMERS WITH PERFLUOROPOLYETHER SEGMENT AND MULTIPLE AMINOOXALYLAMINO GROUPS | 3M INNOVATIVE PROPERTIES CO (US) | 2017-06-28 | — | — | EP | disclosed |
| US-9279035-B2 | Copolymers with perfluoropolyether segment and multiple aminooxalylamino groups | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-03-08 | — | — | US | disclosed |
| EP-2519559-B1 | PERFLUOROPOLYETHER-CONTAINING COMPOUNDS WITH OXALYLAMINO GROUPS | 3M INNOVATIVE PROPERTIES CO (US) | 2015-07-15 | — | — | EP | disclosed |
| US-20150057428-A1 | COPOLYMERS WITH PERFLUOROPOLYETHER SEGMENT AND MULTIPLE AMINOOXALYLAMINO GROUPS | 3M INNOVATIVE PROPERTIES CO (US) | 2015-02-26 | — | — | US | disclosed |
| US-8907120-B2 | Perfluoropolyether-containing compounds with oxalylamino groups | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-12-09 | — | — | US | disclosed |
| US-8907046-B2 | Copolymers with perfluoropolyether segment and multiple aminooxalylamino groups | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-12-09 | — | — | US | disclosed |
| EP-2519564-B1 | COPOLYMERS WITH PERFLUORPOLYETHER SEGMENT AND POLYDIORGANOSILOXANE SEGMENT | 3M INNOVATIVE PROPERTIES CO (US) | 2014-10-22 | — | — | EP | disclosed |
| US-8552124-B2 | Copolymers with perfluoropolyether segment and polydiorganosiloxane segment | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-10-08 | — | — | US | disclosed |
| US-20120289736-A1 | PERFLUOROPOLYETHER-CONTAINING COMPOUNDS WITH OXALYLAMINO GROUPS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-11-15 | — | — | US | disclosed |
| EP-2519559-A2 | PERFLUOROPOLYETHER-CONTAINING COMPOUNDS WITH OXALYLAMINO GROUPS | 3M Innovative Properties Company (US) | 2012-11-07 | — | — | EP | disclosed |
| EP-2519560-A1 | COPOLYMERS WITH PERFLUOROPOLYETHER SEGMENT AND MULTIPLE AMINOOXALYLAMINO GROUPS | 3M Innovative Properties Company (US) | 2012-11-07 | — | — | EP | disclosed |
| EP-2519564-A1 | COPOLYMERS WITH PERFLUORPOLYETHER SEGMENT AND POLYDIORGANOSILOXANE SEGMENT | 3M Innovative Properties Company (US) | 2012-11-07 | — | — | EP | disclosed |
| US-20120264890-A1 | COPOLYMERS WITH PERFLUOROPOLYETHER SEGMENT AND POLYDIORGANOSILOXANE SEGMENT | 3M INNOVATIVE PROPERTIES COMPANY | 2012-10-18 | — | — | US | disclosed |
| US-20120259088-A1 | COPOLYMERS WITH PERFLUOROPOLYETHER SEGMENT AND MULTIPLE AMINOOXALYLAMINO GROUPS | 3M INNOVATIVE PROPERTIES COMPANY | 2012-10-11 | — | — | US | disclosed |
| WO-2011082046-A1 | COPOLYMERS WITH PERFLUORPOLYETHER SEGMENT AND MULTIPLE AMINOOXALYLAMINO GROUPS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011082063-A1 | COPOLYMERS WITH PERFLUORPOLYETHER SEGMENT AND POLYDIORGANOSILOXANE SEGMENT | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011082067-A2 | PERFLUOROPOLYETHER-CONTAINING COMPOUNDS WITH OXALYLAMINO GROUPS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289736-A1 | PERFLUOROPOLYETHER-CONTAINING COMPOUNDS WITH OXALYLAMINO GROUPS | PFAS, PFKFB2, OTC | ALDH1A1 2346/4885THRB 1949/4885BLM 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.