Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30550439 | 0.84 | TP53 (0.47) | RECQLPOLBL3MBTL1LMNAMEN1 | |
| SCHEMBL11650712 | 0.84 | LMNA (0.56) | RECQLL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL21723541 | 0.84 | TP53 (0.47) | RECQLPOLBL3MBTL1LMNAMEN1 | |
| SCHEMBL21723380 | 0.82 | TDP1 (0.51) | RECQLPOLBL3MBTL1LMNAMEN1 | |
| SCHEMBL30550371 | 0.82 | TDP1 (0.51) | RECQLPOLBL3MBTL1LMNAMEN1 | |
| SCHEMBL30550385 | 0.78 | POLB (0.63) | POLBL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL8595564 | 0.78 | POLB (0.63) | POLBL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL11653846 | 0.75 | ALOX15 (0.59) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8354029 | 0.74 | GAA (0.58) | L3MBTL1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL11652878 | 0.71 | GAA (0.61) | L3MBTL1LMNAMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020036386-A1 | ISOINDOLIN-1-ON DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT FOR PREVENTING OR TREATING CANCER | 한국화학연구원 | 2020-02-20 | — | — | WO | disclosed |