Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21732266 | 0.94 | RORC (0.38) | NTRK1JAK2 | |
| SCHEMBL21732214 | 0.92 | RORC (0.36) | NTRK1 | |
| SCHEMBL21732208 | 0.92 | RORC (0.39) | NTRK1 | |
| SCHEMBL21732220 | 0.91 | NTRK1 (0.44) | NTRK1JAK2 | |
| SCHEMBL21732254 | 0.91 | NTRK1 (0.41) | NTRK1JAK2 | |
| SCHEMBL21732265 | 0.91 | RORC (0.41) | — | |
| SCHEMBL21732188 | 0.90 | RORC (0.38) | — | |
| SCHEMBL21732195 | 0.88 | NTRK1 (0.41) | NTRK1JAK2 | |
| SCHEMBL21732206 | 0.88 | RORC (0.37) | — | |
| SCHEMBL21732118 | 0.88 | RORC (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035557-A1 | NOVEL HETEROAROMATIC MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA | LEO PHARMA A/S (DK) | 2020-02-20 | — | — | WO | disclosed |