Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 19/20 | 0.41 |
| ▸ | JAK2 | O60674 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21732259 | 0.87 | NTRK1 (0.41) | NTRK1JAK2 | |
| SCHEMBL21732071 | 0.87 | RORC (0.49) | RORCNTRK1JAK2 | |
| SCHEMBL21732176 | 0.83 | RORC (0.44) | RORCNTRK1JAK2 | |
| SCHEMBL21732180 | 0.78 | RORC (0.47) | RORC | |
| SCHEMBL21732072 | 0.76 | NTRK1 (0.41) | NTRK1JAK2 | |
| SCHEMBL21732284 | 0.75 | RORC (0.49) | RORCNTRK1JAK2 | |
| SCHEMBL21732218 | 0.75 | NTRK1 (0.42) | NTRK1JAK2 | |
| SCHEMBL21732194 | 0.74 | NTRK1 (0.40) | RORCNTRK1JAK2 | |
| SCHEMBL21732118 | 0.73 | RORC (0.51) | RORC | |
| SCHEMBL21732256 | 0.71 | NTRK1 (0.47) | NTRK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035557-A1 | NOVEL HETEROAROMATIC MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA | LEO PHARMA A/S (DK) | 2020-02-20 | — | — | WO | disclosed |