Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21732258 | 0.87 | RORC (0.44) | NTRK1JAK2 | |
| SCHEMBL21732072 | 0.75 | NTRK1 (0.41) | NTRK1JAK2 | |
| SCHEMBL21732071 | 0.74 | RORC (0.49) | NTRK1JAK2 | |
| SCHEMBL21732256 | 0.72 | NTRK1 (0.47) | NTRK1JAK2 | |
| SCHEMBL21732177 | 0.71 | NTRK1 (0.42) | NTRK1JAK2 | |
| SCHEMBL21732262 | 0.68 | NTRK1 (0.54) | NTRK1JAK2 | |
| SCHEMBL21723138 | 0.68 | NTRK1 (0.52) | NTRK1JAK2 | |
| SCHEMBL21732105 | 0.68 | NTRK1 (0.52) | NTRK1JAK2 | |
| SCHEMBL21723176 | 0.67 | NTRK1 (0.47) | NTRK1JAK2 | |
| SCHEMBL17358803 | 0.67 | NTRK1 (0.47) | NTRK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035557-A1 | NOVEL HETEROAROMATIC MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA | LEO PHARMA A/S (DK) | 2020-02-20 | — | — | WO | disclosed |