Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28329487 | 0.79 | ADRA2A (0.48) | ADRA2AHTR2AHTR2CPRMT5RECQL | |
| SCHEMBL31130304 | 0.79 | GRM2 (0.44) | ADRA2AHASPINRECQLKMONOS1 | |
| SCHEMBL7571970 | 0.79 | HASPIN (0.47) | ADRA2AHTR2AHTR2CHASPINRECQL | |
| SCHEMBL30848002 | 0.79 | HASPIN (0.47) | ADRA2AHTR2AHTR2CHASPINRECQL | |
| SCHEMBL31495782 | 0.79 | CYP11B1 (0.42) | ADRA2AHTR2AHTR2CHASPINRECQL | |
| SCHEMBL31750297 | 0.76 | HTR2A (0.47) | ADRA2AHTR2AHTR2CHASPINHTR2B | |
| SCHEMBL19152608 | 0.76 | PRMT5 (0.49) | ADRA2AHTR2AHTR2CPRMT5PSMB8 | |
| SCHEMBL31130114 | 0.75 | XDH (0.41) | ADRA2AHTR2AHTR2CHASPINRECQL | |
| SCHEMBL103561 | 0.75 | ADRA2A (0.44) | ADRA2AHTR2AHTR2CPRMT5RECQL | |
| Ammonia Solution, Strong SCHEMBL5028583 | 0.74 | HASPIN (0.42) | HTR2AHTR2CHASPINRECQLHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402797-B1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2020-02-19 | — | — | EP | disclosed |