Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29323488 | 0.94 | GGPS1 (0.38) | GGPS1ALDH1A1 | |
| SCHEMBL19936946 | 0.82 | GGPS1 (0.41) | GGPS1PIK3CD | |
| SCHEMBL23505460 | 0.80 | GGPS1 (0.48) | GGPS1PIK3CD | |
| SCHEMBL23567936 | 0.80 | LMNA (0.39) | GGPS1PIK3CD | |
| SCHEMBL3429118 | 0.79 | PIK3CD (0.48) | GGPS1ALDH1A1PIK3CD | |
| SCHEMBL27334232 | 0.78 | GGPS1 (0.52) | GGPS1 | |
| SCHEMBL22011331 | 0.78 | CHRM2 (0.44) | GGPS1PIK3CD | |
| SCHEMBL9858530 | 0.77 | TDP1 (0.35) | GGPS1PIK3CD | |
| SCHEMBL22856338 | 0.77 | LMNA (0.41) | GGPS1PIK3CD | |
| SCHEMBL19264171 | 0.77 | GGPS1 (0.46) | GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020037136-A1 | MITRAGYNINE ANALOGS FOR THE TREATMENT OF PAIN, MOOD DISORDERS AND SUBSTANCE USE DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-02-20 | — | — | WO | disclosed |