SCHEMBL22011331

SCHEMBL22011331

CCC(C)CN(C)CCCN

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.44
GGPS1 O95749 3/20 0.32
PIK3CD O00329 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17935182 0.86 CARM1 (0.33) CHRM2PIK3CD
SCHEMBL19936946 0.82 GGPS1 (0.41) GGPS1PIK3CD
SCHEMBL23567936 0.80 LMNA (0.39) GGPS1PIK3CD
SCHEMBL23505460 0.80 GGPS1 (0.48) CHRM2GGPS1PIK3CD
SCHEMBL10704491 0.79 CHRM2 (0.50) CHRM2GGPS1PIK3CDTDP1
SCHEMBL27334232 0.78 GGPS1 (0.52) CHRM2GGPS1
SCHEMBL21733336 0.78 GGPS1 (0.35) GGPS1PIK3CD
SCHEMBL28419369 0.77 CHRM2 (0.48) CHRM2PIK3CDTDP1
SCHEMBL22856338 0.77 LMNA (0.41) CHRM2GGPS1PIK3CD
SCHEMBL19264171 0.77 GGPS1 (0.46) CHRM2GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022147465-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2022-07-07 WO disclosed
US-10662193-B2 Carbazole and carboline compounds for use in the diagnosis, treatment, alleviation or prevention of disorders associated with amyloid or amyloid-like proteins AC IMMUNE SA (CH) 2020-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662193-B2 Carbazole and carboline compounds for use in the diagnosis, treatment, alleviation or prevention of disorders associated with amyloid or amyloid-like proteins APP, BACE1, PSEN1 CHRM2 146/4885GGPS1 3062/4885PIK3CD 4275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.