SCHEMBL21736862

SCHEMBL21736862

CCc1ccc(SC)cc1Br

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 1/20 0.38
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
MCL1 Q07820 1/20 0.36
ALDH1A1 P00352 7/20 0.36
POLB P06746 3/20 0.36
TSHR P16473 2/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
HSD17B10 Q99714 2/20 0.35
SLC6A4 P31645 4/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A3 Q01959 1/20 0.34
MAPT P10636 3/20 0.33
HPGD P15428 2/20 0.33
HRH3 Q9Y5N1 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19743884 0.83 ALDH1A1 (0.37) CRHR1GABRA1GABRB2MCL1ALDH1A1
SCHEMBL24009098 0.82 MCL1 (0.35) CRHR1MCL1ALDH1A1POLBKMT2A
SCHEMBL11737231 0.77 NOX1 (0.33) CRHR1SLC6A4SLC6A2SLC6A3HRH3
SCHEMBL12164519 0.77 ALDH1A1 (0.42) MCL1ALDH1A1POLBTSHRKMT2A
SCHEMBL28245475 0.75 MCL1 (0.48) GABRA1GABRB2MCL1ALDH1A1POLB
SCHEMBL13984183 0.75 MCL1 (0.36) MCL1ALDH1A1POLBTSHRKMT2A
SCHEMBL12164468 0.75 ALDH1A1 (0.45) MCL1ALDH1A1POLBTSHRKMT2A
SCHEMBL882732 0.73 PYCR1 (0.47) GABRA1GABRB2ALDH1A1TSHRMAPT
SCHEMBL24243996 0.72 ALDH1A1 (0.42) MCL1ALDH1A1POLBTSHRKMT2A
SCHEMBL595756 0.72 RHEB (0.36) MCL1ALDH1A1POLBHSD17B10SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611165-A1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2020-02-19 EP disclosed