Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172958 | 0.90 | CNR1 (0.54) | CNR1IGF1RPOLBSLC2A1RAB9A | |
| SCHEMBL2171624 | 0.87 | CNR1 (0.51) | CNR1IGF1RPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL2172966 | 0.87 | SMN1; SMN2 (0.51) | IGF1RSLC2A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL2174484 | 0.84 | IGF1R (0.49) | IGF1RSLC2A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5670028 | 0.82 | IGF1R (0.56) | IGF1RRAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL4395207 | 0.81 | CNR1 (0.51) | CNR1EPHX1IGF1RRAB9AKMT2A | |
| SCHEMBL2171406 | 0.79 | SMN1; SMN2 (0.57) | CNR1IGF1RRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL2174354 | 0.78 | HDAC3 (0.52) | IGF1RRAB9ASMN1; SMN2KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL2173104 | 0.78 | SMN1; SMN2 (0.56) | CNR1IGF1RRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL4393911 | 0.78 | NPC1 (0.54) | EPHX1POLBRAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186905-A1 | ANAPLASTIC LYMPHOMA KINASE MODULATORS AND METHODS OF USE | EXELIXIS, INC. (US) | 2009-07-23 | — | — | US | claimed |
| US-7973061-B2 | Anaplastic lymphoma kinase modulators and methods of use | EXELIXIS, INC. (US) | 2011-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186905-A1 | ANAPLASTIC LYMPHOMA KINASE MODULATORS AND METHODS OF USE | ALK, BCL3, MCL1 | CNR1 1153/4885EPHX1 1420/4885IGF1R 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.