SCHEMBL21736962

SCHEMBL21736962

CC(C)c1nc(F)ccc1Cl

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 2/20 0.33
PNMT P11086 1/20 0.31
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12299834 0.77 GCGR (0.33)
SCHEMBL15077057 0.77 CRHBP (0.39) GLP1RPNMTHTR2AHTR2C
SCHEMBL12434313 0.76 EIF4A3 (0.31) HTR2C
SCHEMBL20780323 0.76 GLP1R (0.34) GLP1RPNMTHTR2AHTR2C
SCHEMBL19913387 0.76 CCR1 (0.37) GLP1RPNMTHTR2AHTR2C
SCHEMBL18562235 0.76 GLP1R (0.34) GLP1RPNMTHTR2AHTR2C
SCHEMBL20285916 0.75 CYP2C19 (0.37)
SCHEMBL20326201 0.74 NOS3 (0.37) GLP1RPNMTHTR2AHTR2C
SCHEMBL31661251 0.74 NOS3 (0.37) GLP1RPNMTHTR2AHTR2C
SCHEMBL23547118 0.71 HPGD (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611165-A1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2020-02-19 EP disclosed