SCHEMBL21737449

SCHEMBL21737449

CCc1c(C)c(C(F)(F)F)nn1C

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.35
GAA P10253 1/20 0.34
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 3/20 0.33
APOBEC3G Q9HC16 3/20 0.33
KMT2A Q03164 2/20 0.33
HPGD P15428 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 2/20 0.33
CYP1A2 P05177 2/20 0.32
CYP2C19 P33261 2/20 0.32
RECQL P46063 1/20 0.31
GABRB3 P28472 1/20 0.31
MAPT P10636 1/20 0.31
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14046049 0.80 KDM4E (0.39) POLBKDM4EKMT2AMEN1LMNA
SCHEMBL15730551 0.80 POLB (0.33) POLBALDH1A1KMT2ALMNACYP1A2
SCHEMBL12124199 0.76 POLB (0.38) POLBALDH1A1KDM4EAPOBEC3GKMT2A
SCHEMBL15730247 0.74 LMNA (0.31) POLBKMT2ALMNA
SCHEMBL12124456 0.74 POLB (0.37) POLBALDH1A1KDM4EAPOBEC3GKMT2A
SCHEMBL12160719 0.74 POLB (0.37) POLBALDH1A1KDM4EAPOBEC3GKMT2A
SCHEMBL11967117 0.73 POLB (0.34) POLBGAAALDH1A1KDM4EAPOBEC3G
SCHEMBL15730597 0.73 LMNA (0.36) ALDH1A1KDM4EKMT2ALMNAMAPT
SCHEMBL13259552 0.73 POLB (0.35) POLBGAAALDH1A1KDM4EKMT2A
SCHEMBL24583921 0.72 PDE10A (0.31) PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611165-A1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2020-02-19 EP disclosed