SCHEMBL21737534

SCHEMBL21737534

CC(C)(C)c1cc(Br)sc1Br

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
ATP2A2 P16615 1/20 0.35
ATP2A3 Q93084 1/20 0.35
CA2 P00918 2/20 0.32
CA1 P00915 1/20 0.32
PTGS1 P23219 2/20 0.32
PTGS2 P35354 2/20 0.32
POLB P06746 1/20 0.31
TYR P14679 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21737787 0.78 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2KDM4ECYP1A2MAPT
SCHEMBL21737619 0.76 MAPT (0.32) ALDH1A1SMN1; SMN2KDM4ECYP1A2MAPT
SCHEMBL21737536 0.76 KDM4E (0.32) ALDH1A1SMN1; SMN2KDM4ECYP1A2MAPT
SCHEMBL21721322 0.72 CNR2 (0.31)
SCHEMBL7497036 0.72 PTPN2 (0.34) ALDH1A1SMN1; SMN2CYP1A2MAPTALOX15
SCHEMBL21721175 0.70 GSK3B (0.33) ALDH1A1ALOX15
SCHEMBL21719916 0.68 POLB (0.30) POLB
SCHEMBL4757898 0.67
SCHEMBL21721209 0.67 BACE1 (0.30)
SCHEMBL21721579 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611165-B1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) 2023-08-16 EP disclosed
EP-3611165-A1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2020-02-19 EP disclosed