SCHEMBL4757898

SCHEMBL4757898

C=CC(F)(F)c1cc(Br)sc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21737534 0.67 ALDH1A1 (0.35)
SCHEMBL4533453 0.67 LMNA (0.34)
SCHEMBL19355006 0.60
SCHEMBL24094415 0.58 HRH4 (0.33)
SCHEMBL252057 0.58 GABRA1 (0.35)
SCHEMBL12987427 0.57 GABRA1 (0.34)
SCHEMBL17240318 0.57 GSK3B (0.30)
SCHEMBL917122 0.57
SCHEMBL23536244 0.57 CA1 (0.42)
SCHEMBL21721322 0.57 CNR2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1279689-B1 Mono-, Oligo and Poly-3-(1,1-difluoroalkyl)thiophenes and their use as charge transport materials MERCK PATENT GMBH (DE) 2008-10-01 EP disclosed
US-6806374-B2 FIELD EFFECT TRANSISTOR, OLED, ELECTROLUMINESCENT DEVICE, RFID TAG, BACKLIGHT, PHOTOVOLTAIC OR SENSOR DEVICE, OR ELECTROPHOTOGRAPHIC RECORDING DEVICE; SECURITY MARKING; CHARGE INJECTION LAYER, PLANARISING LAYER, ANTISTATIC FILM MERCK PATENT GMBH (DE) 2004-10-19 US disclosed
US-20030062509-A1 Mono-, oligo- and poly-3-(1,1-difluoroalkyl)thiophenes and their use as charge transport materials MERCK PATENT GMBH (DE) 2003-04-03 US disclosed
EP-1279689-A2 Mono-, Oligo and Poly-3-(1,1-difluoroalkyl)thiophenes and their use as charge transport materials MERCK PATENT GmbH (DE) 2003-01-29 EP disclosed