Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 18/20 | 0.77 |
| ▸ | CSF1R | P07333 | 15/20 | 0.77 |
| ▸ | KDR | P35968 | 13/20 | 0.77 |
| ▸ | FLT3 | P36888 | 6/20 | 0.77 |
| ▸ | AXL | P30530 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 2/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591945 | 0.85 | PDGFRB (0.83) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL2173813 | 0.84 | PDGFRB (0.83) | PDGFRBCSF1RKDRFLT3AXL | |
| SCHEMBL2174528 | 0.82 | FLT3 (0.64) | PDGFRBCSF1RKDRFLT3AXL | |
| SCHEMBL2175384 | 0.82 | FLT3 (0.64) | PDGFRBCSF1RKDRFLT3AXL | |
| SCHEMBL2173716 | 0.82 | KDR (0.59) | PDGFRBCSF1RKDRFLT3AXL | |
| SCHEMBL2172864 | 0.82 | KDR (0.63) | PDGFRBCSF1RKDRFLT3AXL | |
| SCHEMBL2173631 | 0.81 | KDR (0.69) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL2177387 | 0.79 | KDR (0.59) | PDGFRBCSF1RKDRFLT3AXL | |
| SCHEMBL4981120 | 0.79 | PDGFRB (0.65) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL2173638 | 0.77 | PDGFRB (0.84) | PDGFRBCSF1RKDRFLT3MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973164-B2 | Quinoline derivatives | ASTRAZENECA AB (SE) | 2011-07-05 | — | — | US | claimed |