Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20010803 | 0.86 | ALDH1A1 (0.47) | MAPTRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL29980612 | 0.81 | KMT2A (0.55) | MAPTRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL10175272 | 0.80 | GPR35 (0.63) | MAPTRAB9ANPC1GPR35ALDH1A1 | |
| SCHEMBL5271074 | 0.79 | MAPT (0.53) | MAPTRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL21612061 | 0.77 | MAPT (0.46) | MAPTRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL21612062 | 0.76 | MAPT (0.68) | MAPTRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL1850633 | 0.75 | MAPT (0.44) | MAPTRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL17433897 | 0.74 | PDE4A (0.46) | MAPTRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL28907995 | 0.74 | MAPT (0.65) | MAPTRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL23531551 | 0.72 | MAPT (0.50) | MAPTRAB9ANPC1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3369731-B1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEMICAL LTD (KR) | 2020-02-19 | — | — | EP | disclosed |