Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.46 |
| ▸ | FEM1B | Q9UK73 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20456266 | 0.87 | ALDH1A1 (0.66) | PTGDR2ALDH1A1TSHRHPGDGAA | |
| SCHEMBL20463355 | 0.86 | ALDH1A1 (0.52) | PTGDR2ALDH1A1TSHRHPGDGAA | |
| SCHEMBL21392964 | 0.80 | NPC1 (0.62) | ALDH1A1TSHRHPGDLMNAHTT | |
| SCHEMBL1078031 | 0.77 | PTGDR2 (0.60) | PTGDR2ALDH1A1GAAHTTNPC1 | |
| SCHEMBL5804310 | 0.77 | ALDH1A1 (0.69) | PTGDR2ALDH1A1TSHRHTTNPC1 | |
| SCHEMBL9444664 | 0.77 | PTGDR2 (0.52) | PTGDR2ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL31104078 | 0.77 | FNIP1 (0.58) | PTGDR2ALDH1A1TSHRHPGDGAA | |
| SCHEMBL23126358 | 0.76 | MAOB (0.55) | PTGDR2ALDH1A1TSHRHPGDGAA | |
| SCHEMBL25455175 | 0.75 | KMT2A (0.60) | PTGDR2ALDH1A1HPGDGAALMNA | |
| SCHEMBL23817970 | 0.75 | GPX4 (0.54) | PTGDR2ALDH1A1HPGDLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200054651-A1 | COMPOSITIONS AND METHODS FOR MODULATING PPP2R1A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054651-A1 | COMPOSITIONS AND METHODS FOR MODULATING PPP2R1A | PPP2R1A, PPP3CA, PPP2R2A | PTGDR2 1253/4885ALDH1A1 2930/4885TSHR 1652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.