Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21742326 | 0.85 | BLM (0.43) | SMN1; SMN2HTTLMNABLMCYP2D6 | |
| SCHEMBL21742250 | 0.81 | CYP2D6 (0.40) | SMN1; SMN2HTTLMNABLMCYP2D6 | |
| SCHEMBL21742074 | 0.81 | HDAC6 (0.40) | SMN1; SMN2HTTLMNABLMCYP2D6 | |
| SCHEMBL21742087 | 0.81 | CYP1A2 (0.43) | SMN1; SMN2HTTLMNABLMCYP2D6 | |
| SCHEMBL21742333 | 0.78 | BLM (0.40) | SMN1; SMN2HTTBLMCYP2D6L3MBTL1 | |
| SCHEMBL21742052 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2HTTLMNABLMCYP2D6 | |
| SCHEMBL21742177 | 0.76 | AHR (0.38) | SMN1; SMN2HTTLMNABLMCYP2D6 | |
| SCHEMBL28650533 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNABLMCYP2D6L3MBTL1 | |
| SCHEMBL21742157 | 0.76 | L3MBTL1 (0.47) | SMN1; SMN2LMNABLMCYP2D6L3MBTL1 | |
| SCHEMBL28186562 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTLMNABLMCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611164-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |