Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21742157 | 0.86 | L3MBTL1 (0.47) | SMN1; SMN2L3MBTL1BLMCYP2D6CHRM2 | |
| SCHEMBL21742051 | 0.83 | L3MBTL1 (0.44) | SMN1; SMN2L3MBTL1BLMCYP2D6CHRM2 | |
| SCHEMBL21742049 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2L3MBTL1BLMCYP2D6CHRM2 | |
| SCHEMBL2021130 | 0.81 | HDAC6 (0.40) | SMN1; SMN2L3MBTL1BLMCYP2D6CHRM2 | |
| SCHEMBL21742399 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1BLMCYP2D6ALDH1A1 | |
| SCHEMBL21742326 | 0.80 | BLM (0.43) | SMN1; SMN2L3MBTL1BLMCYP2D6CHRM2 | |
| SCHEMBL21742375 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1BLMCYP2D6ALDH1A1 | |
| SCHEMBL21742346 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1BLMCYP2D6CHRM2 | |
| SCHEMBL21742055 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1BLMCYP2D6CHRM2 | |
| SCHEMBL21742158 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2L3MBTL1BLMCYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109867679-B | Preparation method of piricaconide hydrochloride intermediate | 杭州瀚康生物医药科技有限公司 | 2021-11-30 | — | — | CN | disclosed |