SCHEMBL21742399

SCHEMBL21742399

CC(=O)OC(C)(c1ccccn1)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CETP P11597 6/20 0.40
AHR P35869 1/20 0.40
ALDH1A1 P00352 1/20 0.40
BLM P54132 1/20 0.38
CYP2D6 P10635 1/20 0.38
ABCC9 O60706 1/20 0.37
ABCC8 Q09428 1/20 0.37
KCNJ11 Q14654 1/20 0.37
KCNJ8 Q15842 1/20 0.37
HDAC6 Q9UBN7 1/20 0.36
KDM4E B2RXH2 2/20 0.36
ABCB11 O95342 1/20 0.35
LMNA P02545 1/20 0.35
ESR1 P03372 1/20 0.35
CYP3A4 P08684 1/20 0.35
ADRA2A P08913 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21742051 0.87 L3MBTL1 (0.44) SMN1; SMN2L3MBTL1CETPAHRALDH1A1
SCHEMBL21742375 0.83 SMN1; SMN2 (0.41) SMN1; SMN2L3MBTL1CETPAHRALDH1A1
SCHEMBL21742157 0.80 L3MBTL1 (0.47) SMN1; SMN2L3MBTL1CETPAHRALDH1A1
SCHEMBL28650533 0.80 SMN1; SMN2 (0.47) SMN1; SMN2L3MBTL1CETPAHRALDH1A1
SCHEMBL21742400 0.79 SMN1; SMN2 (0.40) SMN1; SMN2L3MBTL1CETPAHRALDH1A1
SCHEMBL21742363 0.78 AHR (0.45) SMN1; SMN2L3MBTL1CETPAHRALDH1A1
SCHEMBL21742326 0.78 BLM (0.43) SMN1; SMN2L3MBTL1CETPAHRALDH1A1
SCHEMBL21742076 0.78 SMN1; SMN2 (0.39) SMN1; SMN2L3MBTL1CETPAHRALDH1A1
SCHEMBL21742346 0.77 SMN1; SMN2 (0.41) SMN1; SMN2L3MBTL1CETPAHRALDH1A1
SCHEMBL21742049 0.76 SMN1; SMN2 (0.43) SMN1; SMN2L3MBTL1CETPAHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611164-A1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2020-02-19 EP disclosed