Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.78 |
| ▸ | GAA | P10253 | 6/20 | 0.78 |
| ▸ | NPC1 | O15118 | 6/20 | 0.78 |
| ▸ | RAB9A | P51151 | 6/20 | 0.78 |
| ▸ | GLA | P06280 | 4/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | PKM | P14618 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | APP | P05067 | 12/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.67 |
| ▸ | CASP1 | P29466 | 1/20 | 0.67 |
| ▸ | CASP7 | P55210 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854930 | 0.90 | MAPT (0.96) | MAPTKDM4EGAANPC1RAB9A | |
| SCHEMBL1995933 | 0.88 | MAPT (1.00) | MAPTKDM4EGAANPC1RAB9A | |
| SCHEMBL3194266 | 0.85 | MAPT (1.00) | MAPTKDM4EGAANPC1RAB9A | |
| SCHEMBL25026544 | 0.82 | KDM4E (0.67) | MAPTKDM4EGAANPC1RAB9A | |
| SCHEMBL3193978 | 0.82 | MAPT (0.81) | MAPTKDM4EGAANPC1RAB9A | |
| SCHEMBL5906538 | 0.82 | MAPT (1.00) | MAPTKDM4EGAANPC1RAB9A | |
| SCHEMBL13806256 | 0.82 | APP (1.00) | MAPTKDM4EGAANPC1RAB9A | |
| SCHEMBL31219254 | 0.82 | APP (1.00) | MAPTKDM4EGAANPC1RAB9A | |
| SCHEMBL17198993 | 0.81 | MAPT (0.74) | MAPTKDM4EGAANPC1RAB9A | |
| SCHEMBL11778594 | 0.81 | MAPT (0.70) | MAPTKDM4EGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7976954-B1 | Layer by layer self-assembly of large response molecular electro-optic materials by a desilylation strategy | NORTHWESTERN UNIVERSITY (US) | 2011-07-12 | — | — | US | disclosed |
| US-7972542-B1 | Layer by layer self-assembly of large response molecular electro-optic materials by a desilylation strategy | NORTHWESTERN UNIVERSITY (US) | 2011-07-05 | — | — | US | disclosed |
| US-7972542-B1 | Layer by layer self-assembly of large response molecular electro-optic materials by a desilylation strategy | NORTHWESTERN UNIVERSITY (US) | 2011-07-05 | — | — | US | disclosed |
| US-7776235-B1 | Layer by layer self-assembly of large response molecular electro-optic materials by a desilylation strategy | NORTHWESTERN UNIVERSITY (US) | 2010-08-17 | — | — | US | disclosed |
| US-7776235-B1 | Layer by layer self-assembly of large response molecular electro-optic materials by a desilylation strategy | NORTHWESTERN UNIVERSITY (US) | 2010-08-17 | — | — | US | disclosed |
| US-7651777-B1 | composite containing first and second siloxane capping layers of octachlorotrisiloxane; a metal selected from Hf, Ga, In; sorption product of a metal oxide (selected fro Hf2O3, Ga2O3, In2O2) directly on said first capping layer; second capping layer covering oxide layer, azo chromophore layer inbetween | NORTHWESTERN UNIVERSITY (US) | 2010-01-26 | — | — | US | disclosed |
| US-7476345-B2 | Layer by layer self-assembly of large response molecular electro-optic materials by a desilylation strategy | NORTHWESTERN UNIVERSITY (US) | 2009-01-13 | — | — | US | disclosed |
| US-20060088717-A1 | Layer by layer self-assembly of large response molecular electro-optic materials by a desilylation strategy | NATIONAL SCIENCE FOUNDATION | 2006-04-27 | — | — | US | disclosed |
| US-6855274-B1 | Layer by layer self-assembly of large response molecular electro-optic materials by a desilylation strategy | NORTHWESTERN UNIVERSITY (US) | 2005-02-15 | — | — | US | disclosed |