Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21742653 | 0.90 | MAPK14 (0.41) | EDNRACYP2D6CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL21742864 | 0.85 | EDNRA (0.48) | EDNRACYP2D6CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL21742645 | 0.84 | GRM5 (0.43) | EDNRACYP2D6ENPP3ENPP1KDM4E | |
| SCHEMBL21742844 | 0.82 | NOTUM (0.52) | MAPK14KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL21742622 | 0.81 | NOTUM (0.50) | MAPK11MAPK14MAPK13MAPK12KDM4E | |
| SCHEMBL21742855 | 0.79 | LDHA (0.44) | CYP11B1CYP11B2ENPP3ENPP1 | |
| SCHEMBL21742651 | 0.78 | MAPK13 (0.41) | EDNRACYP2D6CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL21742566 | 0.78 | GRM5 (0.43) | CYP2D6MAPK11MAPK14MAPK13MAPK12 | |
| SCHEMBL3157652 | 0.78 | NOTUM (0.52) | CYP2D6CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL31360692 | 0.78 | NOTUM (0.52) | CYP2D6CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | PNMT, DDT, TYR | EDNRA 731/4885CYP2D6 12/4885CHRNB2 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.