SCHEMBL21743200

SCHEMBL21743200

Cc1ccccc1NCC1=CC=CC(C)C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.43
HTT P42858 3/20 0.43
ADRA2C P18825 4/20 0.42
ALDH1A1 P00352 3/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
ADRA2B P18089 2/20 0.40
KDM4E B2RXH2 3/20 0.37
NPC1 O15118 1/20 0.36
PKM P14618 1/20 0.36
RAB9A P51151 1/20 0.36
LMNA P02545 4/20 0.35
ALOX12 P18054 2/20 0.33
POLB P06746 1/20 0.33
MPI P34949 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TP53 P04637 1/20 0.33
GAA P10253 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21763860 0.74 LMNA (0.41) MAPTHTTADRA2CALDH1A1KMT2A
SCHEMBL24060802 0.72
SCHEMBL18405386 0.72
SCHEMBL22764783 0.71
SCHEMBL17697086 0.71
SCHEMBL19264704 0.66
SCHEMBL17463549 0.65 ANPEP (0.36) ALDH1A1LMNA
SCHEMBL18761547 0.64 MAPT (0.70) MAPTHTTADRA2CALDH1A1KMT2A
SCHEMBL3440796 0.64 ADRA2C (0.72) MAPTHTTADRA2CALDH1A1KMT2A
SCHEMBL21122662 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200054741-A1 PEPTIDE-BASED VACCINES, METHODS OF MANUFACTURING, AND USES THEREOF FOR INDUCING AN IMMUNE RESPONSE AVIDEA TECHNOLOGIES, INC. (US) 2020-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200054741-A1 PEPTIDE-BASED VACCINES, METHODS OF MANUFACTURING, AND USES THEREOF FOR INDUCING AN IMMUNE RESPONSE MYD88, ICOS, CD4 MAPT 2145/4885HTT 3053/4885ADRA2C 4821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.