⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13417325 | 0.71 | — | — | |
| SCHEMBL14996062 | 0.70 | DNM1 (0.30) | — | |
| SCHEMBL19113715 | 0.69 | — | — | |
| SCHEMBL19831380 | 0.67 | — | — | |
| SCHEMBL19869001 | 0.66 | — | — | |
| SCHEMBL1043900 | 0.65 | — | — | |
| SCHEMBL21971851 | 0.64 | CA1 (0.31) | — | |
| SCHEMBL22722192 | 0.64 | — | — | |
| SCHEMBL24784950 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL22771776 | 0.64 | FDPS (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11207431-B2 | HDAC6 inhibitors and imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2021-12-28 | — | — | US | disclosed |
| US-20200054773-A1 | HDAC6 Inhibitors and Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2020-02-20 | — | — | US | disclosed |