Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 3/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4228422 | 0.80 | ACACB (0.48) | MMP13 | |
| SCHEMBL942191 | 0.80 | JAK2 (0.55) | BCHEKLK7STS | |
| SCHEMBL20503925 | 0.80 | JAK2 (0.55) | BCHEKLK7STS | |
| SCHEMBL697850 | 0.80 | JAK2 (0.55) | BCHEKLK7STS | |
| SCHEMBL28256693 | 0.79 | KMT2A (0.43) | KMT2AL3MBTL1SIGMAR1CTSLSTS | |
| SCHEMBL28792068 | 0.79 | KMT2A (0.43) | KMT2AL3MBTL1SIGMAR1CTSLSTS | |
| SCHEMBL606732 | 0.79 | CTSL (0.52) | KMT2AL3MBTL1CTSLSTSSYK | |
| SCHEMBL7479137 | 0.79 | PPARA (0.45) | KMT2AL3MBTL1CTSL | |
| SCHEMBL7486941 | 0.77 | USP30 (0.47) | CARM1PRMT6 | |
| SCHEMBL3249107 | 0.77 | STS (0.58) | STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247578-B2 | Process for production of aralkyloxypyrrolidine derivative | KANEKA CORPORATION (JP) | 2012-08-21 | — | — | US | disclosed |
| US-20110224444-A1 | PROCESS FOR PRODUCTION OF ARALKYLOXYPYRROLIDINE DERIVATIVE | KANEKA CORPORATION (JP) | 2011-09-15 | — | — | US | disclosed |
| US-7973176-B2 | Process for production of aralkyloxypyrrolidine derivative | KANEKA CORPORATION (JP) | 2011-07-05 | — | — | US | disclosed |
| EP-1947083-B1 | PROCESS FOR PRODUCTION OF ARALKYLOXYPYRROLIDINE DERIVATIVE | KANEKA CORP (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-20080306283-A1 | Process For Production of Aralkyloxypyrrolidine Derivative | KANEKA CORPORATION (JP) | 2008-12-11 | — | — | US | disclosed |
| EP-1947083-A1 | PROCESS FOR PRODUCTION OF ARALKYLOXYPYRROLIDINE DERIVATIVE | Kaneka Corporation (JP) | 2008-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306283-A1 | Process For Production of Aralkyloxypyrrolidine Derivative | HPD, HAAO, ARL1 | KMT2A 2745/4885L3MBTL1 3608/4885TMEM97 3899/4885 |
| US-20110224444-A1 | PROCESS FOR PRODUCTION OF ARALKYLOXYPYRROLIDINE DERIVATIVE | HPD, HAAO, ARL1 | KMT2A 2745/4885L3MBTL1 3608/4885TMEM97 3899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.