Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.60 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 7/20 | 0.54 |
| ▸ | BACE1 | P56817 | 7/20 | 0.54 |
| ▸ | BCHE | P06276 | 5/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31644812 | 0.85 | OPRM1 (0.58) | OPRM1OPRL1GRIN2BMEN1KMT2A | |
| SCHEMBL31630259 | 0.83 | ACHE (0.51) | OPRM1OPRL1GRIN2BMEN1KMT2A | |
| SCHEMBL31630161 | 0.83 | POLB (0.65) | OPRM1OPRL1GRIN2BMEN1KMT2A | |
| SCHEMBL663239 | 0.82 | GRIN2B (0.74) | OPRM1OPRL1GRIN2BMEN1KMT2A | |
| SCHEMBL20656939 | 0.82 | OPRM1 (0.54) | OPRM1OPRL1GRIN2BMEN1KMT2A | |
| SCHEMBL21744620 | 0.82 | OPRM1 (0.65) | OPRM1OPRL1GRIN2BMEN1KMT2A | |
| SCHEMBL22411271 | 0.81 | GRIN2B (0.53) | OPRM1OPRL1GRIN2BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31629842 | 0.81 | OPRM1 (0.66) | OPRM1OPRL1GRIN2BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2550113 | 0.81 | MEN1 (0.78) | OPRM1OPRL1GRIN2BMEN1KMT2A | |
| SCHEMBL24350665 | 0.80 | GRIN2B (0.49) | OPRM1OPRL1GRIN2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | UNIV EMORY (US) | 2023-04-13 | — | — | US | disclosed |
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | EMORY UNIVERSITY | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | OPRM1 524/4885OPRL1 405/4885GRIN2B 2480/4885 |
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | OPRM1 524/4885OPRL1 405/4885GRIN2B 2480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.