Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2173510 | 1.00 | PPARA (0.39) | PPARAPPARGRXRARXRBCHRNB2 | |
| SCHEMBL2175393 | 0.79 | PPARA (0.43) | PPARAPPARGRXRARXRBALDH1A1 | |
| SCHEMBL2177734 | 0.79 | PPARA (0.43) | PPARAPPARGRXRARXRBALDH1A1 | |
| SCHEMBL2175272 | 0.78 | PPARG (0.49) | PPARAPPARGRXRARXRBALDH1A1 | |
| SCHEMBL2176897 | 0.78 | PPARG (0.49) | PPARAPPARGRXRARXRBALDH1A1 | |
| SCHEMBL1930436 | 0.74 | PPARG (0.42) | PPARAPPARGALDH1A1SMN1; SMN2PPARD | |
| SCHEMBL1930101 | 0.74 | PPARG (0.42) | PPARAPPARGALDH1A1SMN1; SMN2PPARD | |
| SCHEMBL12492687 | 0.71 | BLM (0.46) | PPARABLMMMEPPARDMEN1 | |
| SCHEMBL5149405 | 0.71 | BLM (0.46) | PPARARXRARXRBALDH1A1SMN1; SMN2 | |
| SCHEMBL11121410 | 0.70 | RXRA (0.46) | RXRARXRBALDH1A1SMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973063-B2 | Methods for activating PPAR gamma-type receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-07-05 | — | — | US | disclosed |