Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177734 | 1.00 | PPARA (0.43) | PPARAPPARGLMNAALDH1A1POLB | |
| SCHEMBL2175272 | 0.84 | PPARG (0.49) | PPARAPPARGALDH1A1MAPTRXRA | |
| SCHEMBL2176897 | 0.84 | PPARG (0.49) | PPARAPPARGALDH1A1MAPTRXRA | |
| SCHEMBL2173510 | 0.79 | PPARA (0.39) | PPARAPPARGALDH1A1PPARDRXRA | |
| SCHEMBL2174458 | 0.79 | PPARA (0.39) | PPARAPPARGALDH1A1PPARDRXRA | |
| SCHEMBL28205569 | 0.76 | PPARG (0.56) | PPARAPPARGLMNAALDH1A1PPARD | |
| SCHEMBL11121410 | 0.75 | RXRA (0.46) | ALDH1A1POLBCTDSP1MAPTRXRA | |
| SCHEMBL5149405 | 0.73 | BLM (0.46) | PPARALMNAALDH1A1POLBCTDSP1 | |
| SCHEMBL12492687 | 0.73 | BLM (0.46) | PPARALMNAPOLBCTDSP1PPARD | |
| SCHEMBL2175094 | 0.72 | BLM (0.44) | PPARALMNAALDH1A1POLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973063-B2 | Methods for activating PPAR gamma-type receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-07-05 | — | — | US | disclosed |