SCHEMBL21744609

SCHEMBL21744609

c1cc2c(c(CN3CCOCC3)c1)CCNC2

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A13 Q16696 7/20 0.48
CD44 P16070 1/20 0.45
CYP2C9 P11712 2/20 0.43
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CXCR4 P61073 1/20 0.42
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 1/20 0.42
HRH3 Q9Y5N1 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
NCF1 P14598 1/20 0.38
PIK3CD O00329 2/20 0.38
PIK3C2B O00750 2/20 0.38
MTOR P42345 2/20 0.38
PIK3CG P48736 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24913864 0.88 CYP2A13 (0.53) CYP2A13CYP2C9ALOX15HSD17B10CXCR4
Hydrochloric Acid SCHEMBL29008593 0.87 CYP2A13 (0.51) CYP2A13CYP2C9ALOX15HSD17B10CXCR4
Hydrochloric Acid SCHEMBL30368364 0.87 CYP2A13 (0.51) CYP2A13CYP2C9ALOX15HSD17B10CXCR4
SCHEMBL21646423 0.77 CYP2A13 (0.50) CYP2A13CYP2C9ALOX15HSD17B10CXCR4
SCHEMBL21744251 0.76 KDM4E (0.49) CD44CYP2C9ALOX15HSD17B10ALDH1A1
SCHEMBL21744253 0.76 HRH3 (0.56) KDM4EHRH3CYP2D6
SCHEMBL21744257 0.76 PIK3CD (0.43) CD44KDM4EMEN1KMT2ACYP3A4
SCHEMBL1011153 0.75 CD44 (0.49) CD44CYP2C9ALOX15HSD17B10ALDH1A1
Trifluoroacetic Acid SCHEMBL5778782 0.74 KDM4E (0.41) CD44ALDH1A1KDM4EMEN1KMT2A
SCHEMBL24913969 0.74 HTR6 (0.49) ALDH1A1KDM4ECYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230112832-A1 Chemokine CXCR4 Receptor Modulators and Uses Related Thereto UNIV EMORY (US) 2023-04-13 US disclosed
US-20200054623-A1 Chemokine CXCR4 Receptor Modulators and Uses Related Thereto EMORY UNIVERSITY 2020-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200054623-A1 Chemokine CXCR4 Receptor Modulators and Uses Related Thereto CXCR4, CXCL12, CXCR1 CYP2A13 4545/4885CD44 407/4885CYP2C9 4817/4885
US-20230112832-A1 Chemokine CXCR4 Receptor Modulators and Uses Related Thereto CXCR4, CXCL12, CXCR1 CYP2A13 4545/4885CD44 407/4885CYP2C9 4817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.