Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.56 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30101416 | 0.89 | HRH3 (0.53) | HRH3DRD1DRD4DRD5TIPARP | |
| SCHEMBL383947 | 0.82 | HRH3 (0.61) | HRH3CD274SMN1; SMN2KDM4ETSHR | |
| SCHEMBL14287592 | 0.81 | HRH3 (0.82) | HRH3CD274SMN1; SMN2CYP2D6 | |
| SCHEMBL467681 | 0.81 | HRH3 (0.76) | HRH3CD274CYP2D6 | |
| Hydrochloric Acid SCHEMBL5107481 | 0.81 | HRH3 (0.80) | HRH3CD274SMN1; SMN2CYP2D6 | |
| SCHEMBL30101435 | 0.78 | HRH3 (0.58) | HRH3CD274TIPARPPOLBKDM4E | |
| SCHEMBL4760923 | 0.76 | HRH3 (0.49) | HRH3CD274TIPARPMAOB | |
| SCHEMBL17585080 | 0.76 | HRH3 (0.49) | HRH3CD274MAOB | |
| SCHEMBL21744257 | 0.76 | PIK3CD (0.43) | POLBKDM4ETSHR | |
| SCHEMBL21744609 | 0.76 | CYP2A13 (0.48) | HRH3KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | UNIV EMORY (US) | 2023-04-13 | — | — | US | disclosed |
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | EMORY UNIVERSITY | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | HRH3 2159/4885CD274 446/4885DRD1 4283/4885 |
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | HRH3 2159/4885CD274 446/4885DRD1 4283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.