Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.35 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3474472 | 0.82 | GAA (0.41) | GAACDC25BKCNH2RPS6KA3NFATC1 | |
| SCHEMBL29544825 | 0.82 | GAA (0.41) | GAACDC25BKCNH2RPS6KA3NFATC1 | |
| SCHEMBL84373 | 0.77 | GAA (0.46) | GAACDC25BCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL4408576 | 0.76 | GAA (0.45) | GAACDC25BCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL2108667 | 0.76 | GAA (0.45) | GAACDC25BCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL24037998 | 0.74 | LOXL2 (0.43) | CDC25BRPS6KA3 | |
| SCHEMBL2111078 | 0.74 | GAA (0.43) | GAACDC25BCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL14121041 | 0.74 | LMNA (0.48) | GAACDC25BCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL2495086 | 0.74 | GAA (0.43) | GAACDC25BCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL13028991 | 0.74 | LMNA (0.48) | GAACDC25BCYP3A4CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020037109-A1 | PROCESSES FOR FLUORINATION | DOW AGROSCIENCES LLC (US) | 2020-02-20 | — | — | WO | disclosed |
| CN-109415358-A | 6-aminopyridin-3-ylthiazoles as ROR gamma t modulators | 詹森药业有限公司 | 2019-03-01 | — | — | CN | disclosed |