Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15885693 | 0.83 | MEN1 (0.33) | TRPV4CYP2A13LMNAALOX15CXCR4 | |
| SCHEMBL10247439 | 0.79 | HTR2A (0.51) | DRD2HTR2AHRH1CYP2A13LMNA | |
| SCHEMBL21746420 | 0.74 | KDM4E (0.38) | DRD2HTR2AHRH1CYP2A13LMNA | |
| SCHEMBL10049910 | 0.72 | GAA (0.37) | DRD2HTR2AHRH1ALOX15ALDH1A1 | |
| SCHEMBL21746530 | 0.71 | USP2 (0.54) | ALOX15ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL21747064 | 0.68 | L3MBTL1 (0.35) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL12165181 | 0.67 | GAA (0.38) | DRD2HTR2AHRH1ALOX15ALDH1A1 | |
| SCHEMBL2220561 | 0.67 | HIF1A (0.36) | CYP2A13ALOX15CXCR4ALDH1A1HTT | |
| SCHEMBL24156797 | 0.67 | SMN1; SMN2 (0.51) | ALDH1A1RAB9AMEN1KMT2AUSP2 | |
| SCHEMBL21746548 | 0.65 | CYP2D6 (0.35) | MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |