Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15885535 | 0.83 | USP2 (0.54) | USP2ATMPDE4DCYP2D6HSD17B10 | |
| SCHEMBL21746420 | 0.83 | KDM4E (0.38) | USP2PDE4DCYP2D6KMT2AL3MBTL1 | |
| SCHEMBL21747064 | 0.79 | L3MBTL1 (0.35) | PDE4DCYP2D6HSD17B10KMT2AL3MBTL1 | |
| SCHEMBL10247439 | 0.79 | HTR2A (0.51) | ALDH1A1POLBMAPK1 | |
| SCHEMBL21746548 | 0.76 | CYP2D6 (0.35) | PDE4DCYP2D6KMT2AL3MBTL1MEN1 | |
| SCHEMBL21745887 | 0.74 | KMT2A (0.43) | HSD17B10ALOX15KMT2AMEN1KDM4E | |
| SCHEMBL709506 | 0.74 | USP2 (1.00) | USP2ATMCYP2D6HSD17B10KMT2A | |
| SCHEMBL24707031 | 0.73 | PDE4D (0.61) | USP2PDE4DCYP2D6HSD17B10ALOX15 | |
| SCHEMBL30001517 | 0.73 | PDE4D (0.61) | USP2PDE4DCYP2D6HSD17B10ALOX15 | |
| SCHEMBL21747003 | 0.71 | DRD2 (0.38) | USP2ALOX15MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |