Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21747443 | 0.91 | HSD17B10 (0.58) | SIRT1HSD17B10NPSR1MAPTTP53 | |
| SCHEMBL21747494 | 0.90 | HSD17B10 (0.57) | SIRT1HSD17B10NPSR1MAPTTP53 | |
| SCHEMBL21747493 | 0.88 | SIRT1 (0.51) | SIRT1HSD17B10NPSR1MAPTHPGD | |
| SCHEMBL21747456 | 0.87 | HSD17B10 (0.54) | SIRT1HSD17B10NPSR1MAPTTP53 | |
| SCHEMBL30468278 | 0.87 | HSD17B10 (0.53) | SIRT1HSD17B10NPSR1MAPTTP53 | |
| SCHEMBL21747472 | 0.85 | SIRT1 (0.49) | SIRT1HSD17B10NPSR1MAPTTP53 | |
| SCHEMBL21747479 | 0.84 | SIRT1 (0.57) | SIRT1HSD17B10NPSR1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL21747450 | 0.83 | SIRT1 (0.57) | SIRT1HSD17B10NPSR1MAPTHPGD | |
| SCHEMBL30468245 | 0.80 | SIRT1 (0.64) | SIRT1HSD17B10NPC1RAB9A | |
| SCHEMBL2740314 | 0.80 | SIRT1 (0.60) | SIRT1MAPTTP53HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | Pusan National University Industry - University Cooperation Foundation (KR) | 2020-02-26 | — | — | EP | claimed |
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | disclosed |
| EP-3613735-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | Pusan National University Industry - University Cooperation Foundation (KR) | 2020-02-26 | — | — | EP | disclosed |