Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21748137 | 0.73 | APLNR (0.49) | APLNR | |
| SCHEMBL18246330 | 0.69 | APLNR (1.00) | APLNR | |
| SCHEMBL18247081 | 0.69 | APLNR (1.00) | APLNR | |
| SCHEMBL18246445 | 0.69 | APLNR (1.00) | APLNR | |
| SCHEMBL18245812 | 0.69 | APLNR (1.00) | APLNR | |
| SCHEMBL23549410 | 0.69 | APLNR (1.00) | APLNR | |
| SCHEMBL18247014 | 0.69 | APLNR (1.00) | APLNR | |
| SCHEMBL21328207 | 0.65 | APLNR (0.89) | APLNR | |
| SCHEMBL21767053 | 0.64 | APLNR (0.79) | APLNR | |
| SCHEMBL18254282 | 0.61 | APLNR (0.76) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3300500-B9 | TRIAZOLE AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2021-01-13 | — | — | EP | disclosed |
| EP-3300500-B1 | TRIAZOLE AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2020-02-26 | — | — | EP | disclosed |