SCHEMBL21748753

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30783176	1.00	ALDH1A1 (0.54)	ALDH1A1HPGDSMN1; SMN2MAPTHSP90AA1
	SCHEMBL15797407	0.81	ALDH1A1 (0.50)	ALDH1A1HPGDSMN1; SMN2MAPTHSP90AA1
	SCHEMBL30353352	0.81	ALDH1A1 (0.54)	ALDH1A1HPGDSMN1; SMN2MAPT
	SCHEMBL25556165	0.81	ALDH1A1 (0.54)	ALDH1A1HPGDSMN1; SMN2MAPT
	SCHEMBL2313992	0.78	ALDH1A1 (0.51)	ALDH1A1P2RX7
	SCHEMBL531072	0.78	ALDH1A1 (0.68)	ALDH1A1HPGDSMN1; SMN2MAPTHSP90AA1
	SCHEMBL31639294	0.76	ALDH1A1 (0.49)	ALDH1A1HPGDSMN1; SMN2MAPTHSP90AA1
	SCHEMBL6075377	0.75	TAAR1 (0.50)	HPGDMAPTLMNAMAPK1KDM4E
	SCHEMBL17664582	0.75	CYP3A4 (0.40)	LMNAP2RX7
	SCHEMBL12352043	0.75	LMNA (0.47)	MAPTLMNATDP1P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.