SCHEMBL21749394

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21749446	0.86	THRB (0.59)	THRBTHRAARPARP1
	SCHEMBL24032753	0.86	THRB (0.56)	THRBTHRAAR
	SCHEMBL2922891	0.85	THRB (0.68)	THRBTHRACYP2C9UGT1A1ABCG2
	SCHEMBL21840370	0.78	THRB (0.48)	THRBTHRAPRMT5WDR77
	SCHEMBL24032735	0.77	THRB (0.55)	THRBTHRA
	SCHEMBL21840363	0.75	THRB (0.48)	THRBTHRACYP2C9UGT1A1ABCG2
	SCHEMBL31054376	0.75	THRB (0.46)	THRBTHRA
	SCHEMBL21749488	0.75	THRB (0.48)	THRBTHRAARPARP1
	SCHEMBL38650728	0.75	THRB (0.45)	THRBTHRA
	SCHEMBL24032754	0.75	THRB (0.43)	THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.