Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 13/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 13/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 13/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 13/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2176888 | 0.99 | PLG (0.40) | PLGPRSS1PRSS2PRSS3PTGS2 | |
| SCHEMBL2176885 | 0.99 | PLG (0.40) | PLGPRSS1PRSS2PRSS3PTGS2 | |
| SCHEMBL2175784 | 0.93 | PLG (0.43) | PLGPRSS1PRSS2PRSS3PTGS2 | |
| SCHEMBL2175781 | 0.93 | PLG (0.43) | PLGPRSS1PRSS2PRSS3PTGS2 | |
| SCHEMBL2174447 | 0.92 | PLG (0.42) | PLGPRSS1PRSS2PRSS3PTGS2 | |
| SCHEMBL2174444 | 0.92 | PLG (0.42) | PLGPRSS1PRSS2PRSS3PTGS2 | |
| SCHEMBL2174734 | 0.91 | PTGS2 (0.40) | PLGPRSS1PRSS2PRSS3PTGS2 | |
| SCHEMBL2175533 | 0.90 | PTGS2 (0.40) | PLGPRSS1PRSS2PRSS3PTGS2 | |
| SCHEMBL2175536 | 0.90 | PTGS2 (0.40) | PLGPRSS1PRSS2PRSS3PTGS2 | |
| SCHEMBL3944631 | 0.88 | PLG (0.39) | PLGPRSS1PRSS2PRSS3PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973063-B2 | Methods for activating PPAR gamma-type receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-07-05 | — | — | US | disclosed |