Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2175533 | 0.94 | PTGS2 (0.40) | PTGS2MMEL1HDAC1HDAC6PLG | |
| SCHEMBL2175536 | 0.94 | PTGS2 (0.40) | PTGS2MMEL1HDAC1HDAC6PLG | |
| SCHEMBL2173079 | 0.93 | PTGS2 (0.44) | PTGS2MMEL1PLGPRSS1PRSS2 | |
| SCHEMBL2173074 | 0.93 | PTGS2 (0.44) | PTGS2MMEL1PLGPRSS1PRSS2 | |
| SCHEMBL2174810 | 0.92 | PTGS2 (0.42) | PTGS2MMEL1ITGB3ITGAVLTB4R2 | |
| SCHEMBL2174814 | 0.92 | PTGS2 (0.42) | PTGS2MMEL1ITGB3ITGAVLTB4R2 | |
| SCHEMBL2174985 | 0.91 | PLG (0.42) | PTGS2HDAC1HDAC6PLGPRSS1 | |
| SCHEMBL2174613 | 0.90 | ITGB3 (0.42) | PTGS2HDAC1HDAC6PLGPRSS1 | |
| SCHEMBL2176888 | 0.90 | PLG (0.40) | PTGS2MMEL1PLGPRSS1PRSS2 | |
| SCHEMBL2175701 | 0.90 | PTGS2 (0.38) | PTGS2MMEL1HDAC1HDAC6PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973063-B2 | Methods for activating PPAR gamma-type receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-07-05 | — | — | US | disclosed |